In order to study the effects of aqua-acupuncture with SamGuiRyong-Tang on the adrenocortical insufficiency induced by dexamethasone in rats, animal experiments were carried out. After the rats were induced acute adrenocortocal insufficiency, aqua-acupuncture with SamGuiRyong-Tang were injected into the corresponding loci to Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) of human body and a Blank locus of the root of tail.
Experimental groups were devided into 4 groups ; control group, aqua-acupunture of SamGuiRyong-Tang groups treated on Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) respectively, and Blank locus(BL) group.
Then the serum levels of cortisol, glucose, total cholesterol, and total protein, the serum concentrations of sidium, patassium, and blood urea nitrogen were measured respectively on the 1st and 3rd days.
The obtained results were as follows;
1. The levels of serum cortisol were increased in all the groups, compared with those of the control group, while aqua-acupuncture of SamGui-Ryong-Tang group treated on Sin-Su(Bl_(23)) showed a significant increase on the 3rd day.
2. The levels of serum glcose were increased in all the groups, compared with those of the control group, while aqua-acupuncture of SamGui-Ryong-Tang groups treated an Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) showed significant increases respectively on the 3rd day.
3. The concentrations of serum were increased in all the groups, compared with those of the control gruup, while aqua-acupuncture of Sam-Gui-Ryong-Tang groups treated on Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) showed most significant increases respectively on the 1st and 3rd days.
The concentrations of serum potassium were decreased in all the groups, compared with those of the control grpup, while aqua-acupuncture of Sam-GuiRyong-Tang groups treated on Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) showed significant decreases on the 3rd day.
4. The levels of serum total choleterol were decreased in all the groups, compared with those of the control group, while aqua-acupuncture of SamGuiRyong-Tang groups treated on Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) showed significant decreases on the lst and 3rd day. Especially aqua-acupuncture of Sin-Su(Bl_(23)) group showed most significant decreases on the 3rd day.
5. The levels of serum total protein were increased in all the groups, compared with those of the control group, while SamGuiRyong-Tang group treated on Sin-Su(Bl_(23)) showed a significant increases on the 1st and 3rd days.
6. The concentrations of serum blood urea nitrogen were decreased in all the groups, compared with those of the control group, while SamGuiRyong-Tang groups treated on Sin-Su(Bl_(23)) and Sam-Eum-Gyo(Sp_6) showed significant increases on the 3rd day.
In conclusion, the results of this study seemed to indicate that aqua-acupuncture with SamGuiRyong-Tang respectively at the corresponding loci to Sin-Su(Bl_(2)3) and Sam-Eum-Gyo(Sp_6) were effective on the treatment for acute adrenocortical insufficieency indeced by dexamethasone, and as the efficacies of aquq-acupuncture theraphy, however, depend on not only the effects of drugs but also the effects of acupuncture loci, selection of acupuncture loci and drugs must be considered in clinical practice.
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